吴琴（1990 年 10 月生）
博士讲师
E-mail：397875957@qq.com
个人简历
■教育经历
2014-2019 年，华中农业大学，获理学博士学位
2010-2014 年，湖北师范大学，获理学学士学位
■工作经历
2020.01-今，湖北师范大学生命科学学院任教
研究领域
主要从事水生态毒理与环境保护研究方面的科研工作。具体研究领域包括：
■微囊藻毒素-LR 诱导斑马鱼神经毒性分子机制研究
■纳米毒理学，微囊藻毒素与纳米材料联合毒性效应及机制研究
承担的课程
人体组织学与解剖学理论、人体组织学与解剖学实验、人体及动物生理学、人体及动物生理学实验、生物学综合实验
主持的课题项目
农产品常用杀菌剂戊唑醇对斑马鱼生殖毒性风险评估 （湖北省重点实验室开放基金，2020-2022）
环境浓度微囊藻毒素暴露影响斑马鱼胚胎孵化的分子机制（湖北省自然科学基金青年项目，2021-2023）
抗生素诺氟沙星对斑马鱼胚胎肠道微生物与神经发育的影响 （湖北省教育厅科学研究计划资助项目， 2021-2023）
微囊藻毒素-LR通过干扰下丘脑-垂体轴抑制斑马鱼胚胎孵化的分子机制研究（国家自然科学基金青年基金项目，2023-2025）
代表性成果
■Wu Qin, Gong Aoxue, Liu Xixia, Hou Jianjun, Liu Huan, Yang Zhi and Zhu Ya*. 2024. Probiotics alleviate microcystin-lr-induced developmental toxicity in zebrafish larvae. Toxics, 12.
■Wu Qin#, Li GuangYu#, Huo Tangbin, Du Xue, Yang Qing, Hung Tien-Chieh, Yan Wei*.2021.Mechanisms of parental co-exposure to polystyrene nanoplastics and microcystin-LR aggravated hatching inhibition of zebrafish offspring. Science of the Total Environment, 774,145776.
■Lu Juanli#, Wu Qin#, Yang Qing, Li Guangyu, Wang Ruiqi, LiuYingxin, Duan Cunyu, Duan Shiyun, He Xuanyi, Huang Zhuo, Peng Xitian, YanWei⁎, Jiang Jinhua⁎. Molecular mechanism of reproductive toxicity induced by betacypermethrin in zebrafish.2020. Comparative Biochemistry and Physiology, Part C. 239,108894.
■Wu Qin, Yan Wei*, Liu ChunSheng, Hung Tien-Chieh, Li GuangYu*. 2019. Co-exposure with titanium dioxide nanoparticles exacerbates MCLR-induced brain injury in zebrafish. Science of the Total Environment, 693, 133540.
■Wu Qin, Yan Wei, Liu ChunSheng, Hung Tien-Chieh, Li GuangYu*. 2018. Parental transfer of titanium dioxide nanoparticle aggravated MCLR-induced developmental toxicity in zebrafish offspring.Environmental science: Nano. 5, 2952–2965.
■Wu Qin, Yan Wei, Cheng Houcheng, Liu Chunsheng, Hung Tien-Chieh, Guo Xiaochun, Li Guangyu*. 2017. Parental transfer of microcystin-LR induced transgenerational effects of developmental neurotoxicity in zebrafish offspring. Environmental Pollution, 231, 471–478.
■Wu Qin, Yan Wei, Liu ChunSheng, Li Li, Yu Liqin, Zhao SuJuan, Li GuangYu*. 2016. Microcystin-LR exposure induces developmental neurotoxicity in zebrafish embryo. Environmental Pollution. 213, 793–800.
■Zuo Junli, Huo Tangbin, Du Xue, Yang Qing, Wu Qin, Shen Jianzhong, Liu Chunsheng, Hung Tien-Chieh, Yan Wei, Li Guangyu. The Joint Effect of Parental Exposure to Microcystin-LR and Polystyrene Nanoplastics on the Growth of Zebrafish Offspring. 2020. Journal of Hazardous Materials. 124677.
■Cheng Houcheng, Yan Wei, Wu Qin, Lu Juanli, Liu Chunsheng, Hung Tien-Chieh, Li Guangyu*. 2018. Adverse reproductive performance in zebrafish with increased bioconcentration of microcystin-LR in the presence of titanium dioxide nanoparticles. Environmental Science: Nano. 5, 1208–1217.
■Cheng Houcheng, Yan Wei, Wu Qin, Liu Chunsheng, Gong Xiuying, Hung Tien-Chieh, Li Guangyu*. 2017. Parental exposure to microcystin-LR induced thyroid endocrine disruption in zebrafish offspring, a transgenerational toxicity. Environmental Pollution. 230, 981–988.
■Wang Zhikuan, Li Guangyu, Wu Qin, Liu Chunsheng, Shen Jianzhong*, Yan Wei. 2018. Microcystin-LR exposure induced nephrotoxicity by triggering apoptosis in female zebrafish. Chemosphere. 214, 598–605.
■LiuHaoling, YangQing, LiGuangyu*,Hung Tien-Chieh,ZuoJunli, LuanNing, LiuXiaolin, WuQin. 2024. Probiotic Lactobacillus rhamnosus modulates MCLR-induced oogenesis disorders inzebrafish: evidence from the transcriptome. Science of the Total Environment,951, 175532.
■赵明明，吴琴，成厚城，丁华，王婧，彭立军，严伟．2016. 微囊藻毒素-LR 诱发的甲状腺毒性对斑马鱼胚胎发育的影响．湖北农业科学，55，6525–6528．