肖小月 （1997年8月） 湖北襄阳人
博士 讲师
E-mail：xiaoyuexiao@hbnu.edu.cn
个人简历
■教育经历
2019-2025年，南昌大学，食品科学与工程专业，硕博连读，获工学博士学位。
2023-2024年，University of California，Davis，CSC联合培养。
2015-2019年，南昌大学，食品科学与工程专业，获工学学士学位
■工作经历
2025.7-至今，湖北师范大学生命科学学院任教
研究领域
主要从事食品安全和免疫学快速检测研究的工作。具体研究领域包括：
■食品中危害物免疫识别元件的筛选和识别机理研究。
■生物传感器的开发及应用。
■食品中危害物多靶标检测方法的开发。
承担的课程
暂无
主持和参与的课题项目
■国家自然科学基金《高灵敏多通量荧光淬灭均相免疫分析检测食源性致病菌》（82260644），参与；
■国家自然科学基金《基于颜色阵列复合编码免疫层析的沙门氏菌血清分群新方法学研究》（82003467），参与；
■食品科学与资源挖掘全国重点实验室自由探索资助课题《基于脂质体核心的珊瑚状金纳米球双信号免疫层析法的建立》（SKLF-ZZB-202315），参与。
代表性成果
科研论文
■Xiaoyue Xiao, Zhenzhen Chen, Jiawei Chen, Yanyan Tang, Gan Zhang, Juan Peng, Daofeng Liu, Bruce D. Hammock*, Weihua Lai *. Comparative Analysis of Immunization Strategies for Broad-Specificity Antibody Preparation and Immunoassay Development for Sulfonamides Detection in Chicken and Pork Samples [J]. Food Bioscience, 2025, 67, 106350. (IF=4.8)
■Xiaoyue Xiao, Sha Yu, Gan Zhang, Zongyou Chen, Hong Hu, Xiaocui Lai, Daofeng Liu*, Weihua Lai*. Efficient photothermal sensor based on coral-like hollow gold nanospheres for the sensitive detection of sulfonamides [J]. Small, 2024, 2307764. (IF=13)
■Xiaoyue Xiao, Yanmei Huang, Xuelong Zhao, Huanhuan Bao, Zhongwei Lu, Shan Shan*, Daofeng Liu*, Weihua Lai*. Intelligently identifiable membrane immunochip sensor based on Braille-like code for simultaneous multi-veterinary drug detection [J]. Sensors and Actuators B: Chemical, 2022, 359, 131571. (IF= 8.4)
■Xiaoyue Xiao, Song Hu, Xiaocui Lai, Juan Peng, Weihua Lai*. Developmental trend of immunoassays for monitoring hazards in food samples: A review [J]. Trends in Food Science & Technology, 2021, 111, 68-88. (IF= 16.002)
■ Miaolin Duan, Xiaoyue Xiao (Co-first author), Yanmei Huang, Guoqiang Li, Shan Shan, Xi Lv, Houde Zhou, Silu Peng, Chengwei Liu*, Daofeng Liu*, Weihua Lai*. Immuno-HCR based on contact quenching and fluorescence resonance energy transfer for sensitive and low background detection of Escherichia coli O157:H7 [J]. Food Chemistry, 2021, 334, 127568. (IF= 9.231)
■Xiaoyue Xiao, Chun Wang, Zhen Guo, Debin Guo, Wenhua Lai, Juan Peng*. Gold Nanoparticle-Based Paper Sensor for Highly Specific Detection of Ofloxacin in Beef [J]. Journal of Food Chemistry & Nanotechnology, 2020, 5, 72-78.
■ Shan Shan, Lv Xi, Xiaoyue Xiao, Yanmei Huang, Xiaoyu Tong, Weihua Lai, Chengwei Liu, Shuanglong Wang, Daofeng Liu*. Integrated double signal amplification systems with ELISA assay for sensitive detection of tylosin in food [J]. Food and Agricultural Immunology, 2024, 35(1): 2292971.
■ Zhenzhen Chen, Jiawei Chen, Gan Zhang, Xiaoyue Xiao, Daofeng Liu, Weihua Lai, Juan Peng*. Dual-assist heterologous antigens screening: An effective strategy to improve the sensitivity of lateral flow immunoassay [J]. Food Chemistry, 2024: 141131.
■ Jiawei Chen, Gan Zhang, Xiaoyue Xiao, Daofeng Liu, Juan Peng, Yonghua Xiong, Weihua Lai*. Bifunctional bovine serum albumin modification driven sensitivity-enhanced lateral flow immunoassay for small molecule hazards monitoring in food [J]. International Journal of Biological Macromolecules, 2024: 136915.
■ Xuhan Huang, Gan Zhang, Zhipeng Fang, Xiaocui Lai, Xiaoyue Xiao, Juan Peng, Weihua Lai*. Nanomodification engineering facilitated efficient fluorescence quenchers for developing sensitive lateral flow immunoassay [J]. Chemical Engineering Journal, 2024, 492: 152136.
■ Wenkai Cao, Shan Shan, Keyu Xing, Xudong Jing, Juan Peng, Xiaoyue Xiao, Daofeng Liu*, Jun Xia*, Weihua Lai*. Novel rapid detection of melamine based on the synergistic aggregation of gold nanoparticles [J]. Food Chemistry, 2023, 428: 136789.
■ Yumeng Wang, Gan Zhang, Xiaoyue Xiao, Xinhui Shu, Dan Fei, Yelan Guang, Yaomin Zhou*, Weihua Lai*. High-performance fluorescent microspheres based on fluorescence resonance energy transfer mode for lateral flow immunoassays [J]. Analytical Chemistry, 2023, 95(48): 17860-17867.
■ Xiaocui Lai, Ganggang Zhang, Shengliang Deng*, Gan Zhang, Xiaoyue Xiao, Weihua He, Liu Su, Cong Liu, Weihua Lai*. Triple strategy-enhanced immunochromatographic assay based on APCB and AIEFM for the ultrasensitive detection of AFM1 [J]. Journal of Hazardous Materials, 2023, 460: 132438.
■ Xudong Jing, Shan Shan, Keyu Xing, Wenkai Cao, Xiaoyue Xiao, Daofeng Liu*, Weihua Lai*. Sensitive fluorescence ELISA with streptavidin scaffolded DNA tetrads for the detection of Escherichia coli O157: H7 [J]. Journal of Dairy Science, 2023, 106(9): 5930-5939.
■ Zhongwei Lu, Yanmei Huang, Xiaoyue Xiao, Yining Luo, Jie Liu, Jiaqi Yin, Chengwei Liu, Shan Shan*, Daofeng Liu*, Weihua Lai*. A spatial color co-recognition immunochromatographic assay based on the hue-saturation-brightness color space to classify Salmonella serogroups [J]. Sensors and Actuators B: Chemical, 2023, 383: 133580.
■ Gan Zhang, Hong Hu, Shengliang Deng*, Xiaoyue Xiao, Yonghua Xiong, Juan Peng*, Weihua Lai*. An integrated colorimetric and photothermal lateral flow immunoassay based on bimetallic Ag–Au urchin-like hollow structures for the sensitive detection of E. coli O157: H7 [J]. Biosensors and Bioelectronics, 2023, 225: 115090.
■ Shan Shan, Yanmei Huang, Zhaohong Huang, Zhonger Long, Chengwei Liu, Xuelong Zhao, Keyu Xing, Xiaoyue Xiao, Jintao Liu, Yunhong Huang, Weihua Lai, Daofeng Liu*. Detection of stx1 and stx2 and subtyping of Shiga toxin-producing Escherichia coli using asymmetric PCR combined with lateral flow immunoassay [J]. Food Control, 2021, 126: 108051.
■ Xiaocui Lai, Ganggang Zhang, Lifeng Zeng, Xiaoyue Xiao, Juan Peng, Ping Guo, Wei Zhang, Weihua Lai*. Synthesis of PDA-mediated magnetic bimetallic nanozyme and its application in immunochromatographic assay [J]. ACS Applied Materials & Interfaces, 2020, 13(1): 1413-1423.
■ Song Hu, Jintao Liu, Ganggang Zhang, Zexiang Wang, Xiaoyue Xiao, Danhong Li, Juan Peng, Weihua Lai*. Reliable performance of aggregation-induced emission nanoparticle-based lateral flow assay for norfloxacin detection in nine types of animal-derived food [J]. Talanta, 2020, 219: 121245.
标准制定
■参与制定江西省市场监督管理局发布的第一批量子点层析法地方标准《粮食中黄曲霉毒素 B1、 玉米赤霉烯酮、脱氧雪腐镰刀菌烯醇的检测 量子点微球荧光免疫层析法》（DB36/Z 003—2022）