董卫卫 副教授（博士）

发布者：生命科学学院发布时间：2026-04-01浏览次数：10

个人简历

董卫卫（1992.05）

博士 副教授 硕士生导师 东楚英才

QQ：1570266392

邮箱：weiweidong@hbnu.edu.cn

教育经历：

(1) 2014-09至2020-12，华中农业大学，微生物学，理学博士

(2) 2019-10至2020-09，伊利诺伊大学厄巴纳-香槟分校, Carl R. Woese Institute for Genomic Biology, 微生物学联合培养

(3) 2010-09至2014-06，湖北大学, 生物科学, 理学学士

工作经历：

(1) 2020-12至2023-07，华中农业大学，生物工程 博士后

(2) 2023-07至今，湖北师范大学，生命科学学院 任讲师、副教授

(3) 2023-11至今，高层次人才校企共享计划，劲牌有限公司，企业技术顾问

承担课程：

  1. 本科生课程：微生物学实验，发酵食品创新设计，生物学综合实验

  2. 研究生课程：微生物资源利用与开发，高级微生物学，微生物学专题

研究方向：

  1. 传统发酵微生态与生物大健康：以传统酿造与发酵食品体系为研究对象，系统解析发酵过程中微生物群落的结构演替、群感效应调控及功能互作机制，阐明关键功能菌群驱动风味物质、生物活性代谢物与安全性因子的形成规律，为发酵食品健康功能的科学认知与工艺优化提供理论基础。

  2. 微生物菌种资源研究及应用：面向农业与生物制造需求，系统发掘、鉴定并保藏具有明确功能性状与应用潜力的微生物菌种资源，重点关注其环境适应性、功能稳定性及规模化应用性能；结合基因组学与代谢组学手段，推动优势菌株在农业废弃物高值转化、动物营养与健康调控、作物促生与抗逆等场景中的工程化应用；

  3. 微生物药物与合成生物学：基于合成生物学与代谢工程理论，利用基因编辑与调控网络重构技术，设计高效、可控的微生物细胞工厂，用于新型抗生素、功能酶制剂及高附加值生物活性产物的定向合成，为微生物药物与生物制造提供创新技术路径。

主持项目：

(1) 中国博士后科学基金面上项目，N-酰基高丝氨酸内酯酶高效快速筛选质粒的构建和定向进化(2021M701342)，8万元，结题，主持；

(2) 湖北省自然科学基金，基于相互作用的酵母菌群落平衡和传统固态酿造品质的关系(2025AFB267)，10万，在研，主持；

(3) 农业微生物资源发掘与利用全国重点实验室开放课题，基于清香型白酒酿造酵母互作与品质提升机制研究(AMLKF202508)，5万，在研，主持；

(4) 横向，氨基甲酸乙酯微生物代谢调控机制解析及减控技术研究，4万，在研，主持。

获奖情况：

(1) 我国特色酒曲酿造微生物解析及其在酿造中的应用，2025-12，中国食品工业协会科学技术二等奖；

(2) 传统固态白酒酿造核心功能菌群构建与品控关键技术研发及产业化，2024-03，湖北省科学技术进步二等奖；

(2)指导学生获2025年“湖北省大学生生物实验技能竞赛”一等奖；

(3) 指导学生获得“第九届（2024）湖北省高校大学生酒体设计大赛”二等奖；

(4) 指导学生获得“第八届（2023）湖北省高校大学生酒体设计大赛”二等奖。

代表性论文和专利：

  1. Weiwei Dong; Tianlun Ye; Zongjie Zhang; Longxu An; Yaxuan Peng; Youwei Chen; Yu Zhang; Lu Ke; Shenxi Chen; Shumiao Zhao; Yuanliang Hu*. Quorum sensing-associated acid adaptation in bacterial communities during pit fermentation of sauce-flavor Baijiu, International Journal of Food Microbiology (IF=5.2,中科院一区), 2026,453: 111715.

  2. Weiwei Dong; Shenxi Chen*; Yuanliang Hu*. Editorial: Diversity, function, and application of microbes in the fermentation or production of traditional food, Frontiers in Microbiology (IF=4.0,中科院二区), 2026,16: 1751159.

  3. Weiwei Dong; Yaxuan Peng; Jiyuan Ma; Yuanliang Hu*; Shenxi Chen*; Shumiao Zhao*. Yeasts in traditional Baijiu fermentation: diversity, functions, microbial interactions and applications, Frontiers in Microbiology (IF=4.0,中科院二区), 2025,16: 1652173.

  4. Yaqin Zhang; Yiwen Sun; Guoping Sun; Jun Liu; Yanli Feng; Xiang Yu; Jun Liu; Hongbin Yi; Weiwei Dong*; Yuanliang Hu*; Isolation, identification and characteristics of Clostridium butyricum CB-a together with its high-density fermentation, Biotechnology & Biotechnological equipment, 2025, 39: 2580676.

  5. Dong Weiwei; Zhou Rui; Li Xudong; Yan Hua; Zheng Jinshui; Peng Nan; Zhao Shumiao*; Effect of simplified inoculum agent on performance and microbiome during cow manure-composting at industrial-scale, Bioresource Technology (IF=9.7,中科院一区top), 2024, 393: 130097.

  6. Dong Weiwei†; Yu Xiang†; Wang Luyao; Zou Menglin; Ma Jiyuan; Liu Jun; Feng Yanli; Zhao Shumiao; Yang Qiang; Hu Yuanliang*; Chen Shenxi*; Unveiling the microbiota of sauce-flavor Daqu and its relationships with flavors and color during maturation, Frontiers in Microbiology (IF=4.0,中科院二区), 2024,15: 1345772.

  7. Dong Weiwei; Zeng Yulun; Ma Jiyuan; Cai Kaiyun; Guo Tingting; Tan Guanxun; Yu Xiang; Hu Yuanliang; Peng Nan; Zhao Shumiao*; Characteristics and Functions of Dominant Yeasts Together with Their Applications during Strong-Flavor Baijiu Brewing, Foods (IF=4.7,中科院二区), 2024, 13(15): 2409.

  8. Dong Weiwei†; Zhang Jingjing†; Zou Menglin; Chen Liang; Zhu Liping; Zhang Long; Zhang Gang; Tang Jie; Yang Qiang; Hu Yuanliang*; Chen Shenxi*; High-throughput sequencing analysis of microbiota and enzyme activities in Xiaoqu from seven provinces in southern China, Journal of Microbiology and Biotechnology (IF=2.5,中科院四区), 2024,34(11): 2290-2300.

  9. Dong Weiwei; Fan Zhanlei; Li Panxian; Liu Jun; Sun Guoping; Peng Nan; Liang Yunxiang; Zhao Shumiao*; Optimizing the scale-up production of fermented astragalus and its benefits to the performance and egg quality of laying hens, Frontiers in Microbiology (IF=4.0,中科院二区), 2023, 14: 1165644.

  10. Dong Weiwei; Shen Hongye; Liu Huanming; Song Fei; Li Pu; Peng Nan; Liang Yunxiang; Zhao Shumiao*; Unraveling the microbial community and succession during zha-chili fermentation and their relationships with flavor formation, Food Research International (IF=8.1,中科院一区top), 2022, 157: 111239.

  11. Dong Weiwei; Dong Shengqi; Li Yongxu; Lei Yutian; Peng Nan; Liang Yunxiang; Zhao Shumiao*; Ge Xiangyang*; Comprehensive utilization of palm kernel cake for producing mannose and manno-oligosaccharide mixture and yeast culture, Applied Microbiology and Biotechnology (IF=5.0,中科院二区top), 2022, 106: 1045-1056.

  12. Dong Weiwei; Cai Yuyuan; Xu Zhilong; Fu Biao; Chen Qitong; Cui Yuxin; Ruan Zhiyong; Liang Yunxiang; Peng Nan; Zhao Shumiao*; Heterologous expression of AHL lactonase AiiK by Lactobacillus casei MCJ Delta 1 with great quorum quenching ability against Aeromonas hydrophila AH-1 and AH-4, Microbial Cell Factories (IF=5.3,中科院二区), 2020, 19: 191.

  13. Dong Weiwei†; Yang Qiang†; Liao Yuxiang; Liu Yuancai; Hu Yuanliang; Peng Nan; Liang Yunxiang; Zhao Shumiao*; Characterisation and comparison of the microflora of traditional and pure culture xiaoqu during the baijiu liquor brewing process, Journal of the Institute of Brewing, 2020, 126(2): 213-220.

  14. Dong Weiwei; Zhu Jie; Guo Xiang; Kong Delong; Zhang Qi; Zhou Yiqing; Liu Xiaoyang; Zhao Shumiao*; Ruan Zhiyong*; Characterization of AiiK, an AHL lactonase, from Kurthia huakui LAM0618(T) and its application in quorum quenching on Pseudomonas aeruginosa PAO1, Scientific Reports, 2018, 8: 6013

  15. Dong Weiwei†; Kong Delong†; Zhang Qi†; Zhu Jie; Wang Yanwei; Song Jinlong; Zhou Yiqing; Jiang Xu; Zhang Wei; Zhao Shumiao*; Ruan Zhiyong*; Chitinophaga salinisoli sp nov., isolated from saline soil, Antonie van Leeuwenhoek, 2018, 111: 265-273

  16. 阮志勇；董卫卫；赵述淼；赵君才；王彦伟；张琪；江旭；周义清；孔德龙；一种N-酰基高丝氨酸内酯酶及其药物，2020-6-9，中国，CN201710448157.4(专利)

  17. 赵述淼；顿耀豪；董卫卫；梁运祥；葛向阳；彭楠；一种复合乳酸菌制剂及在制备成饲料添加剂中的应用，2021-3-5，中国，ZL201911211156.3(专利)

  18. 赵述淼；蔡玉缘；顿耀豪；董卫卫；梁运祥；彭楠；葛向阳；梅余霞；一株可高效利用菊芋粉的副干酪乳杆菌及其应用，2022-4-1，中国，CN111944730 B(专利)